Section: New Software and Platforms

In silico

In silico design of nanoparticles for the treatment of cancers by enhanced radiotherapy

Keywords: Bioinformatics - Cancer - Drug development

Functional Description: To speed up the preclinical development of medical engineered nanomaterials, we have designed an integrated computing platform dedicated to the virtual screening of nanostructured materials activated by X-ray making it possible to select nano-objects presenting interesting medical properties faster. The main advantage of this in silico design approach is to virtually screen a lot of possible formulations and to rapidly select the most promising ones. The platform can currently handle the accelerated design of radiation therapy enhancing nanoparticles and medical imaging nano-sized contrast agents as well as the comparison between nano-objects and the optimization of existing materials.

• Participant: Thierry Bastogne

• Contact: Thierry Bastogne